Zinc-Deficiency Pellagra-Like Dermatitis—A Rare Complication Following Bariatric Bypass Surgery: A Case Report

Department of General Surgery, Mackay Memorial Hospital, Taipei, Taiwan

*Corresponding author: Dr. Po-Chun Wang, Department of General Surgery, Mackay Memorial Hospital, No. 45, Minsheng Rd., Tamsui Dist., New Taipei City, Taiwan (R.O.C.), Tel: +886-2-2809-4661, Fax: +886-2-2809-4679, E-mail: [email protected]

Received Date: July 25, 2025

Publication Date: September 09, 2025

Citation: Pei-Hsin W, et al. (2025). Zinc-Deficiency Pellagra-Like Dermatitis—A Rare Complication Following Bariatric Bypass Surgery: A Case Report. Nutraceutical Res. 4(1):13.

Copyright: Pei-Hsin W, et al. © (2025).

ABSTRACT

Objectives: To highlight the risk of micronutrient deficiencies, particularly zinc deficiency, following Roux-en-Y gastric bypass (RYGB) surgery and emphasize the importance of clinical vigilance in identifying such complications. Methods: A case report of a 37-year-old woman who underwent RYGB in June 2014 is presented. Her postoperative progress, symptoms, clinical findings, and diagnostic process were documented and analyzed. Results: The patient achieved significant weight loss and BMI reduction within six months post-surgery. However, she developed symptoms including hair loss, erythematous skin lesions on her extremities, and photosensitivity. Severe diarrhea further complicated the presentation. A diagnosis of zinc-deficiency pellagra-like dermatitis was made. Symptoms resolved following intravenous zinc sulfate treatment. Conclusion: Zinc and other micronutrient deficiencies are common but often under-recognized complications after bariatric surgery. Laboratory findings may not always reflect clinical status. Early recognition through physical examination and prompt treatment are essential. A multidisciplinary approach is necessary to optimize postoperative care and prevent long-term sequelae.

Keywords: Bariatric Surgery, Complications, Micronutrients, Niacin Deficiency, Pellagra-Like Dermatitis, Zinc Deficiency